|
KMID : 0604520090350010057
|
|
Journal of the Society of Cosmetic Scientists of Korea
2009 Volume.35 No. 1 p.57 ~ p.63
|
|
|
Anti-aging and Anti-melanogenesis Efficacy by Antioxidative Mineral-bio Water
|
|
Choi Hyun-Kyung
Oh Myoung-Jin
Her Myeong-Jun
Kyeong Kyeong-Hwan
Park Chang-Seo
|
|
|
Abstract
|
|
|
|
UV irradiated skin cells produce reactive oxygen species (ROS). ROS is known to be the primary cause of skin inflammation that is eventually leading to skin aging through decrease of collagen in the dermis. In this study, we evaluated basic efficacy of anti-aging, anti-inflammation and anti-melanogenesis using two antioxidative mineral-bio waters (Mineral-bio water 1 (MIBA-W1) and Mineral-bio water 2 (MIBA-W2)). Both antioxidative mineral-bio waters reduced TNF- expression which was induced upon UV irradiation. MIBA-W 1 increased collagen synthesis from UVB irradiated fibroblast at 0.01 % concentration but MIBA-W2 shows slight, but linear increase. Stimulation of melanogenesis by -MSH treatment in the cultured B16-F1 melanoma was significantly reduced by the treatment of MIBA-W2 in a dose dependent manner. Taken together, antioxidative MIBA-W1 and 2 seem to have potential applications as functional cosmetic materials.
|
|
|
KEYWORD
|
|
|
antioxidative mineral-bio water, TNF-, collagen synthesis, melanin, B16-F1 melanoma
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|